Pleckstrin-2

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August undefined, 2024

Webb24 aug. 2024 · However, the molecular events regulating HNSCC tumorigenesis remain poorly understood. Therefore, uncovering the underlying mechanisms is urgently needed to identify novel and promising therapeutic targets for HNSCC. In this study, we aimed to explore the role of pleckstrin-2 (PLEK2) in regulating HNSCC tumorigenesis. Methods Webb3 dec. 2015 · Plek2 is an actin binding protein, like pleckstrin-1, contains a central DEP domain known to bind RacGTPase, is Epo dependent, and is expressed in all stages of terminal erythropoiesis. We evaluate plek2 mRNA and protein expression in sorted bone marrow erythroid precursors from WT, th1/th1, and transferrin-treated th1/th1 mice.

PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING PROTEIN, …

Webb3 maj 2024 · We identify pleckstrin-2-a STAT5-dependent lipid binding protein downstream of erythropoietin-as an important regulatory node. We demonstrate that partial loss of … WebbSymbol: Plek2: Name: pleckstrin 2: RGD ID: 1305786: Description: Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; phosphatidylinositol-3,5 ... hcl technologies nehru place address

PLEK2 - en-academic.com

Webb21 mars 2024 · PLEK (Pleckstrin) is a Protein Coding gene. Diseases associated with PLEK include Aarskog-Scott Syndrome and Agammaglobulinemia, X-Linked . Among its related … Webb17 aug. 2009 · A passionate Certified Health Professional and Research thought-leader with 15 years of tangible experience in the management and oversight of research … Webb17 nov. 2024 · Pleckstrin-2 is a member of pleckstrin family with well-defined structural features that was first identified in 1999. Over the past 20 years, our understanding of … hcl technologies netherlands

Cells Free Full-Text The Epac1 Protein: Pharmacological …

Webb2 dec. 2016 · Role of Activated Pleckstrin-2 and Down-Stream Effects on Ineffective Erythropoiesis in β-Thalassemic Mice Blood American Society of Hematology … WebbProvided below are ELISA kits targeting pleckstrin 2, a human protein encoded by PLEK2. This protein is 353 amino acids long with a reported mass of 40 kDa. This is reported to … hcl technologies nagpur mihan addressWebb21 mars 2024 · PLEK2 (Pleckstrin 2) is a Protein Coding gene. Diseases associated with PLEK2 include Ecthyma and Anemia, Congenital Dyserythropoietic, Type Iiia . An … gold cooking utensil set

"WebbPleckstrin homology (PH) domains are small modules of approximately 120 amino acids that are found in many proteins involved in cell signaling and other membrane … " - Pleckstrin-2

Pleckstrin-2

WebbFERM, ARHGEF And Pleckstrin Domain-Containing Protein 1 (FARP1) Antibody. REQUEST MORE INFO . Catalogue No: abx430207. Price: £295.00 (Size: 200 µl) Reviews: (0 … Webb17 nov. 2024 · Pleckstrin-2 is a member of pleckstrin family with well-defined structural features that was first identified in 1999. Over the past 20 years, our understanding of …

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Webb3 maj 2024 · We identify pleckstrin-2—a STAT5-dependent lipid binding protein downstream of erythropoietin—as an important regulatory node. We demonstrate that … WebbThe lack of therapeutic alternatives for the treatment of Chagas disease, a neglected disease, drives the discovery of new drugs with trypanocidal activity. Consequently, we …

WebbPleckstrin 2: Predicted location i Intracellular: Number of transcripts i. 3: HUMAN PROTEIN ATLAS INFORMATION i ... Iron-sulfur cluster assembly 2: 0.5503: 46: VTI1B: Vesicle … Webb30 juli 1999 · Pleckstrin 1 is a substrate of multiple isoforms for PKC, and its phosphorylation has been used as an early marker of platelet activation. We have …

WebbPLEK2. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … WebbAnti-PLEKHA4 antibody produced in rabbit. Synonym (s): Anti-PEPP1, Anti-pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4. …

WebbThe lack of therapeutic alternatives for the treatment of Chagas disease, a neglected disease, drives the discovery of new drugs with trypanocidal activity. Consequently, we conducted in vitro studies using UBMC-4, a potential Trypanosoma cruzi AKT-like pleckstrin homology (PH) domain inhibitory compound found using bioinformatics tools. … hcl technologies new delhi addressWebb5 aug. 2024 · Pleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 … gold cookware and bowlsWebbHuman diseases caused by Plek2 mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in … hcl technologies newarkWebb29 mars 2024 · Pleckstrin 2 is a potential drug target for colorectal carcinoma with activation of APC/betacatenin. TGF-beta-induced PLEK2 promotes metastasis and … hcl technologies new jerseyWebb5 feb. 2024 · Background It has been reported that Pleckstrin 2 (PLEK2) acts as an oncogene in non-small cell lung cancer (NSCLC). Bromodomain containing protein 4 … gold cookware setWebb29 nov. 2024 · In addition, Epac1 facilitates Ca 2+ exchange from the endoplasmic reticulum (ER) to the mitochondrion by enhancing the formation of a Ca 2+-handling macromolecular complex composed of voltage-dependent anion channel 1 (VDAC1), the chaperone glucose-regulated protein 75 (GRP75), and the inositol-1,4,5-trisphosphate … hcl technologies njWebbThe world's first wiki where authorship really matters. Due credit and reputation for authors [authorship tracking technology]. Imagine a global collaborative knowledge base for … gold cookware