Cd172a 心肌
WebIt belongs to the Ig superfamily and is primarily expressed on monocytes/macrophages, granulocytes, dendritic cells, and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and ... WebCD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces ...
Cd172a 心肌
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WebMar 21, 2024 · GeneCards Summary for FAM172A Gene. FAM172A (Family With Sequence Similarity 172 Member A) is a Protein Coding gene. Diseases associated with FAM172A … WebDescription: This P84 monoclonal antibody reacts with mouse CD172a, also known as signal regulatory protein a (SIRPa). This cell surface glycoprotein consists of three Ig-like extracellular domains and two cytoplasmic …
WebSignal-regulatory protein alpha. Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by … Web靶向性突变干扰素-β及其用途,202480043176.7,发明授权,本发明部分地涉及包含突变干扰素‑β的嵌合蛋白质及其作为治疗剂的用途。,龙图腾网是一站式知识产权交易服务,专利技术转让,发明专利转让交易,商标专利交易平台,提供专利出售转让服务,专注专利买卖,商标专利交易转让,商标在线公证,汇聚上 ...
Web天然免疫细胞上的免疫检查点. SIRPα. SIRP的中文全称是信号调节蛋白(Signal regulatory proteins,又称CD172a, PTPNS1, MFR, p84, BIT, SHPS-1)，SIRPα是SIRP家族中的一个典型抑制性免疫受体，其与配体CD47结合从而阻止巨噬细胞吞噬健康细胞，癌细胞也可以借此逃过免疫系统监视。 WebCD172a is an adhesion molecule of the Ig superfamily which is expressed on neurons in the central nervous system and the retina, on macrophages, and on bone-marrow myeloid …
Web肝癌细胞株；LM3图片MET Others Cynomolgus 食蟹猴 / 恒河猴 c-MET / HGFR 人细胞裂解液 (阳性对照). 肺成纤维细胞 Many types of cells 包装： 5 × 105 次方 (1ml). 人成骨肉瘤细胞;MG-63. 豚鼠心肌细胞;GP-H1 EBV 转化的绒猴白细胞， B95-8 细胞 MEL 细胞，小鼠红白血病细胞. 人胚肺成纤维细胞;MRC-5. SIRPA Others Human 人 SIRPA ...
WebCD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion, and phagocytosis. CD47 (IAP) is the extracellular ligand for CD172a. cramps in inner thighWebCD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline … diy nest thermostatWebFeb 7, 2024 · Abstract. FAM172A, as a newly discovered gene, is little known in cancer development, especially in pancreatic cancer (PC). We investigated the potential role … diy nesting dolls craftWebThe SE5A5 monoclonal antibody specifically binds to a common epitope on CD172a/SIRPα (90 kDa) and CD172b/SIRPβ1 (50 kDa). These transmembrane glycoproteins are members of the Signal Regulatory Protein (SIRP) family that, in turn, belongs to the Immunoglobulin superfamily. The SIRP family is comprised of two subgroups, SIRPα and SIRPβ that are … diy nest thermostat installationWebPerCP-eFluor® 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5. PerCP-eFluor® 710 emits at 710 nm and is excited with the blue laser (488 nm). Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter ... cramps in inner thigh areaWeb1.一种工程化细胞外囊泡，其包含： 至少一种融合多肽，其包含： (i)至少一个感兴趣的蛋白质(POI)结构域或其片段；和 (ii)至少一个囊泡靶向结构域， 其中所述POI结构域位于相对于所述细胞外囊泡的脂质膜的细胞外位置。 2.如权利要求1所述的工程化细胞外囊泡，其中所述细胞外囊泡是外泌体。 cramps in luteal phaseWebCD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D. diy netherlands